Percocet has become one of the routinely abused drugs in United States. Percocet tablets contain a combination of acetaminophen and Oxycodone. Acetaminophen is a non-salicylate antipyretic and analgesic. Oxycodone is the semi-synthetic opioid. The main effects produced by Percocet are euphoria, analgesia and pleasant feelings. By acting on the receptors in the brain, it changes the functioning of the brain. The user shortly develops the dependence on the drug. Anyone who uses the drug in crushed form, chews, snorts, or injects into the vessels has more chances of harmful effects on the body and a higher potential for addiction and overdose. A proper monitoring and treatments are required to overcome this addiction in the rehabilitation centers.