Codeine is a popular drug commonly prescribed by the doctors to manage different levels of pain: mild, moderate or severe. It is also available in the syrup form as an ingredient of the cough suppressants and painkillers. Codeine belongs to the class opiates, also known as a narcotic drug. The other opiates include oxycodone, morphine, and heroin. It was first found in small concentrations in the opium plant, which was then isolated in 1832 by the scientist ‘Robequete’. Discovery of codeine was a revolution in the field of analgesics and antitussives. The addictive potential of Codeine was soon noticed and the pharmaceutical companies and drug manufacturers started adding the warning labels on the over-the-counter medicines containing the drug. Cough syrups containing codeine are available under the brand names ‘Robitussin’ ‘Maxiflu CDX’ and ‘Maxiflu CD’. The drug has a significant addictive and toxic potential, the misuse or taking inappropriate doses of Codeine can lead to addiction, overdose or even death. A proper rehabilitation program becomes mandatory in cases of addiction.