Hydromorphone also called as dihydromorphinone comes under a brand name ‘Dilaudid’. It belongs to the opioid class of drugs and has an almost similar mechanism of action as morphine. To state more accurately, Hydromorphone is a ‘hydrogenated ketone’ derivative of Morphine. Dilaudid is an analgesic that is used to control the pain of moderate to severe intensity. It is mostly used in the hospitals in intravenous form as the bioavailability of drug gets significantly reduced in oral forms. The drug carries a high potential for abuse and addiction. Moreover, the potency is stronger than morphine. It also produces more severe adverse effects like dizziness, hallucinations, hormonal imbalances, and neurotoxicity. It is important to clear the traces of drug particles in order to ward-off these negative effects. The detoxification process is based on the half-life, which further depends on the route used for drug administration.